Description

IsoMut2py is an easy-to-use tool for the detection and postprocessing of mutations from raw NGS sequencing data. It takes sets of aligned reads (BAM files) as its input and can explore and compare the karyotypes of different samples, detect single nucleotide variations (SNVs), insertions and deletions (indels) in single or multiple samples, optimize the identified mutations whenever provided with a list of control samples, plot mutation counts and spectra on readily interpretable charts and decompose them to predefined reference signatures.